منابع مشابه
Oxygen in Biology and Biochemistry: Role of Free Radicals
A free radical is defined as any atom or molecule that contains unpaired electrons and has independent existence (hence, the term free). A dot is used to represent a free radical species. The abstraction or gain of one electron by a nonradical molecule may (or may not) convert it to a radical species. Free radicals can have positive, negative, or neutral charges [reactions (12.1.1) and (12.1.2)].
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Redox reactions play key roles in intra- and inter-cellular signaling, and in adaptative processes of tissues towards stress. Among the major free radicals with essential functions in cells are reactive oxygen species (ROS) including superoxide anion (O2 (•-)), hydroxyl radical ((•)OH) and reactive nitrogen species (RNS) such as nitric oxide ((•)NO). In this article, we review the forgotten and...
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It has become clear since the workshop that free radicals are implicated not only in the promotion phase of carcinogenesis but during initiation as well. Since the workshop, however, despite intriguing trapping studies with Superoxide disimilase. catalase, and Cu-DIPS [copper(II)(3,5-diisopropylsalicylate)2] and generation of OJ using xanthine oxidase, little substantive evidence has been obtai...
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There has been considerable interest in free radicals and their control by extracts of medicinal herbs. This article reviews the advances made in this frontier area of research.
متن کاملFree Radicals in Cardiovascular Diseases
During the past several years, there has been a growing interest in the medical implications of free radicals. These chemical entities are common by-products of many oxidative biochemical reactions in the cell. Free radicals are essential to a number of normal biochemical and physiological processes. They are too reactive to be tolerated in living tissue, and aerobic organisms use sophisticated...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1994
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12374036